Aug 05, 2019 Views: 3510
Èhjeähdj ksid we;sjk jl=.vq frda. iqjlrkak mq¿jka
wo iudcfha frda. .ek l;d lrk fldg jl=.vq frda.h nyq,j wykak" olskak ,efnk frda.hla' fuh ksoka.; jl=.vq frda. fjkak mq¿jka' fndfydaÿrg oeka jeä jeäfhka fmkakqï lrkafka ukqIHhdf.a mßirh fjkiaùu ksid fuu frda.h we;sjk ;;a;ajhla' Bg fyd|u WodyrKh jkafka W;=r W;=re ueo m<d;aj, lDIs ridhk o%jH NQñhg fh§u ksid" thg c,h ñY% ù c,h mdkh lsÍu;a" tu NQñ j, ksmojk fnda. mßfNdackh ksid;a ñksiqka fuu frda.hg f.dÿre ùuhs' fuh uyd jHikhla'
ukqIHhdj fïjdhska fírd.kak ksis C%udkql+, ls%hdud¾.hla f.k we;s njla fmfkkak keye' jl=.vq frda.Ska ixLHdj jeä m<d;a j, ta fjkqfjka frday,la yokjd' tys jrola keye' kuq;a th fkdfjhs fuhg we;s ms<s;=r frda.h iE§uhs j<lajd .; hq;af;a' wdhq¾fõofha m%;sm;a;sh thhs' fláfhkau lshkjd kï frda.h we;sjk fya;=j bj;alr.; hq;=uhs'
fmdfydr iykdOdrhg uu úreoaOhs' bka isoaOlrkafka wvq .dkg ñksiaiqkag fmdfydr §,d" mi;a úkdY lr,d" ñksiaiqkaj;a úkdY jqKd' fï iykdOdrh ,ndfokak ;snqfKa lDIs ridhksl fmdfydr ,nd.ekSug fkdfõ' iajNdúl fmdfydr ,nd.ekSughs' iajNdúl fmdfydr Ndú;hg f.dùkaj Èßu;a l< hq;=hs' wm l=vd ld,fha§ wm ÿgqjd l=Uqre wdÈfha wiajkq ireùug mig f.ß lgq ñY% lrkjd'
ys;kak" W;=re ueo iuyr mjq,a j, idudðlfhda 4 la 5 la bkakjd jl=.vq frda.hg ,laù ñka tl mjq,lg tl jl=.vq frda.sfhl= ysáfhd;a fjkafka uyd úkdYhla' uq;% fmÍfï fõ.h 60] g wvq mqoa.,fhla jl=.vq frda.sfhl= f,i i<lkjd' fuys 60] lsh, idudkH ñksiqka w;r jHjydr jk l:dj' ñka úoHdkql+, woyi kï jl=.vqjl C%shdldÍ;ajh M1/MlN ñks;a;=jlg uq;% msgjk ñ,s,Sg¾ `.Kkhs' kjH úoHd;aulj EGFR - th 60 g wvqùu jl=.vq frda.sfhla fia i,lkjd' tu EGFR 15 g wvqjQ úg reêr ldkaÿlrKh fyda jl=.vq noaO lsÍug fhduqlrkjd'
udOHhg úYd, j.lSula ;sfhkjd fuu Nhdkl wjodku .ek ck;dj oekqj;a lrkak' oeka frday,aj,g .sys,a, n,kakflda' tla wfhla reêr ldkaÿlrKh lr,d odkfldgu wfkla tlaflkdj;a odkjd' frday,aj, f,Ùvq msß,d' fïl cd;sl jHikhla'
Wmam;a;sfhkau jl=.vq frda.sfhl= ùfï yelshdj b;du wvqhs' tu m%udKh jl=.vq frda.Skaf.a m%udKfhka 2] - 5] la ú;r fjkjd' fuu frda.Skaf.a jl=.vq m%udKfhka l=vd ùu fyda jhiska uqyql=rd hk úg jl=.vq wdndO biau;= ùu isÿfjkjd'
;jo wo ffjoH úoHdfõ Nephrotic Syndrome hkqfjka jl=.vq frda. pC%hka .ek wykak ,efnkjd' idudkH whl=g fuh wjfndaO lr.kak mq¿jka jkafka uq;%d iu. wêlj fm%daàka msgùuhs' fuys§ isÿjkafka jl=.vqfõ l=vd reêr kd,sld fmdl=re j,g ydksùfuka'
kuq;a Wm;ska fyda miqj fyda we;sjk jl=.vq wdndO hk folgu fhdod.kakd m%;sldr C%u fndfydau iudkhs' wdhq¾fõo m%;sldr C%ufha§ n,kafka frda.hg wod, fya;=j ke;s lsÍuhs' Èhjeähdj ksid fm%daàka hkjd kï wfma C%ufhka yd ngysr ffjoH C%ufhka flfrk m%;sldr C%u fjkia'
fndfyda fj,djg fjk;a frda.j,g .kakd T!IO ksid ñksiqka jl=.vq wl¾ukH ùug f.dÿre fjkjd' Èhjeähdj úfYaIhs' jl=.vq wl¾ukHh ùug m%;sldr ,nd.ekSug tk frda.Skaf.ka 80] lau Èhjeähd frda.Ska' idudkHfhka Èhjeähdj ksid 10] lska muK jl=.vq ÿ¾j, fjkak mq¿jka' Èhjeähdj md,kh lsÍug ,ndfok fuu fuÜfmdñka" bkaishq,ska hk T!IO ksid tu ÿ¾j,ùu 60] ;a 70] ;a w;r w.hlg <.d fjkjd' fldf,diagfrda,a md,khg ,ndfok wefgdajdiafgáka jl=.vq wl¾ukH ùug fya;= fjkjd' th jd¾;d we;sj fmkajkak wmg idlaIs ;sfhkjd'
óg wu;rj fm%daàk wêl wdydr nyq,j wdydrh .ekSfuka fm%daàk j, ffcùh C%shdj,sfha wka;¾M,h f,i ksmojk C%shákhska ksid •laKD& jl=.vq wl¾ukH ùu isÿfjkjd' kqjr jl=.vq tallfha m%Odkshd fmkajd § ;sfnkjd jl=.vq noaO lrkak tk whf.ka jeäfokd Èhjeähd frda.Ska nj' jl=.vq frda.sfhl= m%;sldr ,nd.ekSug wm fj;g meñKs úg" m<uqfjkau tu frda.shdf.a uq;%d fmrk fõ.h •EGFR& kQ;k ffjoHdkql+,j uek n,kjd' tu w.h 60] g jvd wvq kï tu mqoa.,hd jl=.vq frda.sfhl= f,ihs i,lkafka' fujeks frda.Skag wm T!IO ,ndfokjd' b;d blaukska tu w.h 60] blauùug i<iajkjd' Bg miqj jl=.vq wl¾uKH ùu ksid YÍrfha fjk;a wjhj j, isÿjQ wdndO j,g m%;sldr lrkjd' yDofha we;sjk wdndO ñka úfYaIhs'
wm ta .ek miqj l;d lruq'
wfma m%;sl¾u j,§ tu frda.hg wod< fya;=ldrKh wm bj;a lrkjd' WodyrKhla úÈyg fldf,iagfrda,a frda.sfhl= wm <.g wdjdu tu mqoa.,hdf.a wdydr rgdj wm ksjerÈ lrkjd' tu ksid ngysr T!IO Ndú; lsÍug fndfydaúg isÿjkafka keye' T!IO Ndú;h ksid jl=.vq wdndO j,g f.dÿre jQ frda.Ska wmf.a m%;sldr ,nd.ekSfuka miqj 100] la ksfrda.S ;;a;ajhg m;afjkjd' tfy;a ;ud Ôj;ajk mßirfha n,mEï ksid jl=.vq frda. j,g ,lajQ mqoa.,hka 100] la ksfrda.S lsÍug yelsjkafka keye' tfy;a Tjqka mj;sk ;;a;ajhg idfmalaIj frda.S núka uqod .ekSug wmf.a m%;sldr j,g yelshdj mj;skjd'
óg wu;rj wfma frda.Skaj wms wdOHd;añlj hym;a udkisl;ajfhka mj;ajd .ekSug Èßu;a lrkjd' WodyrKhla f,i fndaê jkaokdj lshkak mq¿jka' wd.ï fNaohlska f;drj fndaê jkaokdj wms frda.Skag fhdackd lrkjd'
ta ukao ñksidg jeäfhkag Tlaiscka ,efnk .y fnda.y'
ug fuu ldrKdj oek.kak ,enqfKa jl=.vq wjidk wêhrfha reêr ldkaÿ lrKh lrmq frda.sfhl=f.a ìß| ;u wdp¾h Wmdêh i|yd ksnkaOkhg fnda.y f;dardf.k ;snqKd' tu wh tu ksnkaOkfha uQ,sl yrh fnda.fhka jeäu Tlaiscka ,efnk nj igyka lr ;snqKd'
jl=.vq frda.shdg wjidkfha§ isÿjkafka reêrh wvqjk .ukau Tlaiscka wvqùuhs' oeka uu tu frda.Ska wdhq¾fõofhka fnda.y <.g hjkj' m%:sM, b;du id¾:lhs'
fndaêh" b;d úYd, m%udKfhka mßirhg Tlaiscka imhkjd' jl=.vq frda.shlg le,aishï ,nd.ekSu wjYH fjkjd' kuq;a tu le,aishï YÍrhg wjfYdaIKh ùu i|yd úgñka ü wjYH fjkjd' b;ska wms wfma frda.Skag fhdackd lrkjd úgñka ü ,nd.ekSu i|yd WoEik ysre t<shg ksrdjrKh fjkak lsh,d'
wêl reêr mSvkh lshkakafka frda.hl ,laIKhla' fldf,diagfrda,a md,kh i|yd Ndú;d lrk wefgdajdiafgáka ksid;a jl=.vqjg ydksjkjd' ta nj f,dal fi!LH ixúOdkh olajk jd¾;d j,skau ikd: fjkj' oeka fldf,iagfrda,a we;s whg wê reêr mSvkh we;s fjkak mq¿jka' ta whg wêreêr mSvkh fok T!IO ksid;a jl=.vqj,g ydksjkjd'
2018 jif¾ wfma%,a 23 jeksod .re;r iajdóka jykafia kula wm <.g jeähd' Wkajykafia wm <.g jäk fldg tÈk Wkajykafiaf.a isrï lshegkska ^Serum Creatanine& lshk mod¾:h ;snqfKa 1'9 f,ihs' isrï lshegkska jeäjkafka YÍrfha uq;%d fmfrk fõ.h wvqjk úghs' thg kùk úoHd;aulj lshkafka EGFR f,ihs' th ;snqfKa 39 hs' uq;%d fmfrk fõ.h wvqfjkak wvqfjkak reêrfha úI jeäfjkjd' uq;%d fmfrk fõ.h jeäfjk fldg f,a j, isrï lshegkska jeäfjkjd' túg f,aj, úi wvqfjkjd' jl=.vqjla lshkafka YÍrfha nysi%dùh o%jH neyer lrk bkao%shla' tys fmfrk fõ.h jeäfjk úg f,aj, úi wvqfjkjd' wms Wkajykafiag i;s fofla fnfy;a ÿkakd' i;s fofla fnfy;a bjrfj,d 2018'05'05 jeksod" ta lshkafka ojia fod<ylska ú;r Wkajykafiaf.a isrï lshegkska 1'9 isg 1'11 olajd wvqjqKd' túg fmfrk fõ.h ^EGFR& 75'40 olajd jeäjqKd' B<.g Wkajykafiaf.a f,a mÍlaId lrkafka 2018'07'30 jeksod' todg lshegkska tl 1'02 olajd wvqù ;snqKd' uq;%d fmfrk fõ.h •EGFR& tl 84 olajd jeäjqKd' fï jf.a wfmka m%;sldr wrka jl=.vq frda. iqjm;a lr .;a whf.a f;dr;=re ish .Kkla wmg idlaIs iys;j fokak mq¿jka'
idlÉPqd lf<a - jika; ,shkf.a